- Joaquin Phoenix Johnny Cash
- Reese Witherspoon June Carter
- Ginnifer Goodwin Vivian Loberto
- Robert Patrick Ray Cash
- Dallas Roberts Sam Phillips
- Dan John Miller Luther Perkins
- Larry Bagby Marshall Grant
- Shelby Lynne Carrie Cash
- Tyler Hilton Elvis Presley
- Waylon Payne Jerry Lee Lewis
- Shooter Jennings Waylon Jennings
- Johnathan Rice Roy Orbison
- Lucas Till joven Jack Cash
- Sandra Ellis Lafferty Maybelle Carter
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