- Forest Whitaker Charlie Archenault
- Dakota Fanning Anne Hagen
- Kate Beckinsale Carla Davenport
- Guy Pearce Dr. Bruce Laraby
- Josh Hutcherson Jimmy Jaspersen
- Jennifer Hudson Kathy Hammet
- Jeanne Tripplehorn Doris Hagen
- Embeth Davidtz Joan Laraby
- Jackie Earle Haley Bob Jaspersen
- Hayley McFarland Lori Carline
- Troy Garity Ron Abler
- Robin Weigert Lydia Jaspersen
- Tim Guinee Aaron Hagen
- James LeGros Dr. Dan Howard
- Walton Goggins Zack
- Randall Park Resident
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