- Ben Stiller Larry Daley
- Amy Adams Amelia Earhart
- Owen Wilson Jedediah
- Hank Azaria Kahmunrah
- Christopher Guest Ivan El Terrible
- Alain Chabat Napoleón Bonaparte
- Ricky Gervais Dr. McPhee
- Steve Coogan Octavio
- Bill Hader General Custer
- Robin Williams Teddy Roosevelt
- Thomas Lennon Wilbur Wright
- Dick Van Dyke Cecil
- Jake Cherry Nick Daley
- Mizuo Peck Sacajawea
- Rami Malek Ahkmenrah
- Patrick Gallagher Attila the Hun
- Jon Bernthal Al Capone
- Craig Robinson
- Ed Helms
- Clint Howard
- Mindy Kaling Docent
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