- Renée Zellweger Roxie Hart
- Catherine Zeta-Jones Velma Kelley
- Richard Gere Billy Flynn
- Queen Latifah Matron Morton
- John C. Reilly Amos
- Christine Baranski Mary Sunshine
- Taye Diggs Líder de la banda
- Lucy Liu Kitty
- Chita Rivera
- Dominic West Fred Casely
- Colm Feore Harrison
- Ekaterina Chtchelkanova The Hunyak
- Mya Mona
- Denise Faye Annie
- Deidre Goodwin June
- Susan Misner Liz
- Jayne Eastwood Sra. Borusewicz
