- Jude Law Dr. Jonathan Banks
- Rooney Mara Emily Taylor
- Catherine Zeta-Jones Dr. Erica Siebert
- Channing Tatum Martin Taylor
- Vinessa Shaw Deidre Banks
- Mamie Gummer Kayla
- Kerry O'Malley Ward Psychiatrist
- David Costabile Carl
- Marin Ireland
- Scott Shepherd NYPD Detective
Cinemanía > Películas > Efectos secundarios > Reparto