- Paul Rudd Scott Lang / Ant-Man
- Evangeline Lilly Hope van Dyne / The Wasp
- Michelle Pfeiffer Janet Van Dyne / Wasp
- Michael Douglas Dr. Hank Pym
- Laurence Fishburne Dr. Bill Foster / Goliath
- Hannah John-Kamen Ava / Ghost
- Walton Goggins Sonny Burch
- Judy Greer Maggie Lang
- Bobby Cannavale Paxton
- Michael Peña Luis
- Randall Park Jimmy Woo
- T.I. Dave
- Goran Kostic Anitolov
- David Dastmalchian Kurt
- Madeleine McGraw Hope (joven)
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