- Ryan Gosling Neil Armstrong
- Claire Foy Janet Armstrong
- Jason Clarke Edward Higgins White
- Kyle Chandler Deke Slayton
- Corey Stoll Buzz Aldrin
- Ciarán Hinds Bob Gilruth
- Lukas Haas Mike Collins
- Pablo Schreiber Jim Lovell
- Christopher Abbott Dave Scott
- Patrick Fugit Elliott See
- Shea Whigham Gus Grissom
- Cory Michael Smith Roger Chaffee
- Brian d'Arcy James Joseph A. Walker
- Ethan Embry Pete Conrad
- Steve Coulter Guenter Wendt
