- Martin Lawrence Roy McCormick / Preacher Don
- Wendy Raquel Robinson Jeanie Ellis
- Breckin Meyer Tim Fink
- Horatio Sanz Sr. Newirth
- Patrick Warburton Larry Burgess
- Megan Mullally Principal Walsh
- Steven Anthony Lawrence Ralph
- Cody Linley Larry Burgess Jr.
- Katt Williams
- Alia Shawkat Amy
