- Tom Cruise Barry Seal
- Sarah Wright Lucy Seal
- Domhnall Gleeson Agente Schafer
- Jesse Plemons Sheriff Downing
- Lola Kirke Judy Downing
- Caleb Landry Jones JB
- Jayma Mays Dana Sibota
- Jed Rees Louis Finkle
- E. Roger Mitchell Agente Craig McCall
- Alejandro Edda Jorge Ochoa
- Benito Martinez James Rangel
- Jayson Warner Smith Bill Cooper
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